The opening chapter of the Resource Book outlines the scope of the document and addresses the relevance of studying exercise in general as well as the specific question, why study exercise in animals? It explains how the suggestions about the use of animals in exercise paradigms contained in the APS Resource Book fit into the context of U.S. animal welfare requirements, including the Animal Welfare Act, the Public Health Service Policy on Humane Care and Use of Animals, and the ILAR Guide for the Care and Use of Laboratory Animals. Specifically, the APS Resource Book is intended to promote an informed dialogue that can help researchers and their IACUCs arrive at satisfactory answers to questions about how to assure the welfare of animals in exercise research protocols. To this end, the APS Resource Book includes 399 reference citations.
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